Shared Decision Making
Treatment Options for Low-Risk (Slow-Growing) Prostate Cancer
This decision aid is for people with prostate cancer who are at low risk of cancer spreading. Low risk is Stage T1 or T2a, Gleason score 6 or lower, and prostate-specific antigen (PSA) level lower than 10 ng/mL.
About Prostate Cancer: The prostate is a gland below the bladder that helps make semen. Cancer is when cells grow in abnormal ways.
Patient Questions
What does the option involve?
What are my chances of surviving prostate cancer for 5 years?
What are the short-term side effects?
- Pain or blood while peeing.
- Not being able to pee.
- Diarrhea or rectal pain.
- Leaking pee.
- Not being able to pee.
- Bleeding.
- Blood clots.
- Infection.
What are the long-term side effects?
- Sexual problems.
- Higher risk for certain types of cancer.
- Sexual problems.
- Leaking pee.
- Trouble peeing.
When will I return to my usual activities?
Definitions
Prostate biopsy: A healthcare professional will use a needle to take samples of the prostate.
Cancer Stage T1 or T2a: It is when the cancer has not spread outside of the prostate. The cancer is growing slowly.
Gleason score: This measure tells how likely the cancer is to spread.
PSA (prostate-specific antigen): PSA is a protein made by the prostate. The PSA level is the amount of PSA in your blood.
References
- American Cancer Society. Radiation Therapy for Prostate Cancer. American Cancer Society website. Updated Mar 28, 2025. Accessed Jul 2, 2025. https://www.cancer.org/cancer/types/prostate-cancer/treating/radiation-therapy.html
- American Cancer Society. Surgery for Prostate Cancer. American Cancer Society website. Updated Nov 22, 2023. Accessed Mar 14, 2025. https://www.cancer.org/cancer/types/prostate-cancer/treating/surgery.html
- Cleveland Clinic. Brachytherapy. Cleveland Clinic website. Updated Nov 18, 2024. Accessed Mar 24, 2025. https://my.clevelandclinic.org/health/treatments/16500-brachytherapy
- Cleveland Clinic. External Beam Radiation Therapy (EBRT). Cleveland Clinic website. Updated Jun 30, 2025. Accessed Jul 16, 2025. https://my.clevelandclinic.org/health/treatments/24008-external-beam-radiation-therapy-ebrt
- Cleveland Clinic. Prostatectomy. Cleveland Clinic website. Updated Oct 9, 2022. Accessed Mar 7, 2025. https://my.clevelandclinic.org/health/treatments/24294-prostatectomy
- DynaMedex. Prostate Cancer. DynaMedex website. Updated Jun 12, 2025. Accessed Jul 2, 2025. https://www.dynamedex.com/condition/prostate-cancer
- DynaMedex: Management of Localized or Locally Advanced Prostate Cancer. DynaMedex website. Updated Jun 26, 2025. Accessed Jul 2, 2025. https://www.dynamedex.com/management/management-of-localized-or-locally-advanced-prostate-cancer
- Hamdy FC, Donovan JL, Lane JA, Metcalfe C, Davis M, Turner EL, Martin RM, Young GJ, Walsh EI, Bryant RJ, Bollina P, Doble A, Doherty A, Gillatt D, Gnanapragasam V, Hughes O, Kockelbergh R, Kynaston H, Paul A, Paez E, Powell P, Rosario DJ, Rowe E, Mason M, Catto JWF, Peters TJ, Oxley J, Williams NJ, Staffurth J, Neal DE, ProtecT Study Group. Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer. N Engl J Med. 2023 Apr 27;388(17):1547-1558 full-text
- Johns Hopkins Medicine. Brachytherapy. Johns Hopkins Medicine website. Accessed Mar 7, 2025. https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/brachytherapy
- Johns Hopkins Medicine. Prostatectomy: What to Expect During Surgery and Recovery. Johns Hopkins Medicine website. Accessed Mar 7, 2025. https://www.hopkinsmedicine.org/health/conditions-and-diseases/prostate-cancer/prostatectomy-what-to-expect-during-surgery-and-recovery
- Mayo Clinic. Active surveillance for prostate cancer. Mayo Clinic website. Updated Nov 15, 2023. Accessed Mar 13, 2025. https://www.mayoclinic.org/tests-procedures/active-surveillance-for-prostate-cancer/about/pac-20384946
- Mayo Clinic. Prostate biopsy. Mayo Clinic website. Updated Apr 30, 2025. Accessed Jul 14, 2025. https://www.mayoclinic.org/tests-procedures/prostate-biopsy/about/pac-20384734
- Mayo Clinic. Prostatectomy. Mayo Clinic website. Updated Sep 7, 2024. Accessed Feb 13, 2025. https://www.mayoclinic.org/tests-procedures/prostatectomy/about/pac-20385198
- National Cancer Institute Hormone Therapy for Prostate Cancer. National Cancer Institute website. Updated Oct 4, 2024. Accessed Feb 17, 2025. https://www.cancer.gov/types/prostate/prostate-hormone-therapy-fact-sheet
- National Cancer Institute. Surveillance, Epidemiology, and End Results Program. SEER*Explorer. National Cancer Institute website. Updated Jul 2, 2025. Accessed Jul 16, 2025. https://seer.cancer.gov/statistics-network/explorer/application.html?site=1&data_type=1&graph_type=2&compareBy=sex&chk_sex_3=3&chk_sex_2=2&rate_type=2
- University of California San Francisco Health. FAQ: Radiation Therapy for Prostate Cancer. University of California San Francisco Health website. Accessed Feb 14, 2025. https://www.ucsfhealth.org/education/faq-radiation-therapy-for-prostate-cancer#